Glycated Hemoglobin A1c and Diabetes Complications

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Short Communication Glycated Hemoglobin “A1c” and Diabetes Complications

Objectives: This study aimed to highlight the association of HbA1c with diabetic related complications. Material and Methods: This retrospective study has been conducted in endocrinology department of Alnoor Specialist Hospital, Makkah, Saudi Arabia, from January 2007 to December 2009. Data has been collected from diabetic patients’ files that were referred to the diabetes outpatient department...

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Hemoglobin A1c in Diabetes: Panacea or Pointless?

Glycation is the nonenzymatic attachment of a monosaccharide to amino groups of proteins. The reaction has been recognized for many years in the food industry, where it is known as browning (also termed the Maillard reaction) and is responsible for the formation of commonly ingested items, such as toast. In patients with diabetes, glucose accumulation results in enhanced glycation of many prote...

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Plasma glucose plays a key role in the complications of diabetes mellitus. Hemoglobin A1c (HbA1c) and circulating concentrations of advanced glycation end products (AGEs) are central to diabetes clinical care and pathophysiology. However, there is evidence for variation between individuals in the relationship of plasma glucose to both these measures and to specific complications. The glycation ...

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ژورنال

عنوان ژورنال: American Journal of Biomedical Sciences

سال: 2012

ISSN: 1937-9080

DOI: 10.5099/aj120200153